141 research outputs found

    H−H-convergence result for nonlocal elliptic-type problems via Tartar's method

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    In this work we obtain a compactness result for the H−H-convergence of a family of nonlocal and nonlinear monotone elliptic-type problems by means of Tartar's method of oscillating test functions.Comment: In this revision we added a new section that shows the Gamma-convergence of the associated energy functional

    An optimal mass transport approach for limits of eigenvalue problems for the fractional pp-Laplacian

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    We find interpretation using optimal mass transport theory for eigenvalue problems obtained as limits of the eigenvalue problems for the fractional p−p-Laplacian operators as p→+∞p\to +\infty. We deal both with Dirichlet and Neumann boundary conditions.Comment: 20 page

    Asymptotic Behaviours in Fractional Orlicz–Sobolev Spaces on Carnot Groups

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    In this article, we define a class of fractional Orlicz–Sobolev spaces on Carnot groups, and in the spirit of the celebrated results of Bourgain–Brezis–Mironescu and of Maz’ya–Shaposhnikova, we study the asymptotic behaviour of the Orlicz functionals when the fractional parameter goes to 1 and 0

    Asympyotic behavior of Musielak-Orlicz-Sobolev modulars

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    In this article we study the asymptotic behavior of anisotropic nonlocal nonstandard growth seminorms and modulars as the fractional parameter goes to 1. This gives a so-called Bourgain-Brezis-Mironescu type formula for a very general family of functionals. In the particu\-lar case of fractional Sobolev spaces with variable exponent, we point out that our proof asks for a weaker regularity of the exponent than the considered in previous articles

    Probing quantum and classical turbulence analogy through global bifurcations in a von K\'arm\'an liquid Helium experiment

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    We report measurements of the dissipation in the Superfluid Helium high REynold number von Karman flow (SHREK) experiment for different forcing conditions, through a regime of global hysteretic bifurcation. Our macroscopical measurements indicate no noticeable difference between the classical fluid and the superfluid regimes, thereby providing evidence of the same dissipative anomaly and response to asymmetry in fluid and superfluid regime. %In the latter case, A detailed study of the variations of the hysteretic cycle with Reynolds number supports the idea that (i) the stability of the bifurcated states of classical turbulence in this closed flow is partly governed by the dissipative scales and (ii) the normal and the superfluid component at these temperatures (1.6K) are locked down to the dissipative length scale.Comment: 5 pages, 5 figure

    Population Immunity against Serotype-2 Poliomyelitis Leading up to the Global Withdrawal of the Oral Poliovirus Vaccine: Spatio-temporal Modelling of Surveillance Data

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    Background Global withdrawal of serotype-2 oral poliovirus vaccine (OPV2) took place in April 2016. This marked a milestone in global polio eradication and was a public health intervention of unprecedented scale, affecting 155 countries. Achieving high levels of serotype-2 population immunity before OPV2 withdrawal was critical to avoid subsequent outbreaks of serotype-2 vaccine-derived polioviruses (VDPV2s). Methods and Findings In August 2015, we estimated vaccine-induced population immunity against serotype-2 poliomyelitis for 1 January 2004–30 June 2015 and produced forecasts for April 2016 by district in Nigeria and Pakistan. Population immunity was estimated from the vaccination histories of children 70% population immunity among children <36 mo old. Districts with lower immunity were clustered in northeastern Nigeria and northwestern Pakistan. The accuracy of immunity estimates was limited by the small numbers of non-polio AFP cases in some districts, which was reflected by large uncertainty intervals. Forecasted improvements in immunity for April 2016 were robust to the uncertainty in estimates of baseline immunity (January–June 2015), vaccine coverage, and vaccine efficacy. Conclusions Immunity against serotype-2 poliomyelitis was forecasted to improve in April 2016 compared to the first half of 2015 in Nigeria and Pakistan. These analyses informed the endorsement of OPV2 withdrawal in April 2016 by the WHO Strategic Advisory Group of Experts on Immunization

    Impact of inactivated poliovirus vaccine on mucosal immunity: implications for the polio eradication endgame.

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    The polio eradication endgame aims to bring transmission of all polioviruses to a halt. To achieve this aim, it is essential to block viral replication in individuals via induction of a robust mucosal immune response. Although it has long been recognized that inactivated poliovirus vaccine (IPV) is incapable of inducing a strong mucosal response on its own, it has recently become clear that IPV may boost immunity in the intestinal mucosa among individuals previously immunized with oral poliovirus vaccine. Indeed, mucosal protection appears to be stronger following a booster dose of IPV than oral poliovirus vaccine, especially in older children. Here, we review the available evidence regarding the impact of IPV on mucosal immunity, and consider the implications of this evidence for the polio eradication endgame. We conclude that the implementation of IPV in both routine and supplementary immunization activities has the potential to play a key role in halting poliovirus transmission, and thereby hasten the eradication of polio
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